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ENCYSIVE
PHARMACEUTICALS (ENCY) discovers, develops and commercializes novel,
synthetic, small molecule compounds to address unmet medical needs. The firm’s
research focuses on the treatment and prevention of interrelated diseases of
the vascular endothelium and exploit the firm’s expertise in the area of
the intravascular inflammatory process, referred to as the inflammatory
cascade, and vascular diseases.
Encysive develops Argatroban, which is used
for the treatment of heparin-induced thrombocytopenia. It completed
Phase 3 development of the endothelin receptor antagonist known as Thelin
for the treatment pulmonary arterial hypertension. The drug was approved
in March 2007 in Australia. The company provides research and development
programs for various cardiovascular and inflammatory diseases.
Collaboration agreements: With Mitsubishi
Pharma; Glaxo SmithKline, plc; and Schering-Plough.
The company was founded in 1989 and is headquartered
in Houston, Texas. To learn more visit: http://www.encysive.com.
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