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Stocks >> Stocks Details

ACTC
 
EMBRYONIC STEM CELL TREATMENT
ADVANCED CELL TECHNOLOGY
 
  Formerly called ATC Holdings Inc., Advanced Cell Technology became a publicly traded company in a reverse merger with Two Moons Kachinas, a manufacturer of Hopi kachina dolls. Advanced Cell Technology is a researcher in regenerative medicine through application of its ACTCellerate human embryonic stem cell technology. The company has three products in the discovery phase of development. It acquired the intellectual property assets of its former competitor Infigen, Inc. relating to somatic cell nuclear transfer (SCNT), parthenogenesis, and other related technologies.

A total of 26 issued patents and numerous pending patent applications were acquired for a combination of cash and shares of common stock. The acquisition provides ACTC with exclusive ownership rights to critical technologies in regenerative medicine and the merger of assets is expected to strengthen ACTC's intellectual property position in the drive towards commercialization of embryonic stem cell and SCNT technology.

Infigen's had filed some of the earliest and most strategic patents in fundamental steps related to SCNT. One such critical step in SCNT is the activation of oocytes - a process designated "parthenogenetic activation". Egg cells must be activated for SCNT to be successful. In a previous royalty-bearing cross license, ACTC acquired freedom to operate under the Infigen patents in the field of human cell therapy. However, with this acquisition, royalty obligations are removed and ACTC owns the patents exclusively for building its business in regenerative medicine and for use in licensing animal applications.

 

The patents following the merger include fundamental technologies useful in the production of any type of cell or tissue matched to the patient through the process of SCNT," said Dr. Michael West, ACTC's President and Chief Scientific Officer. "In addition, the portfolio provides the firm with a dominant patent position in the production of human embryonic stem cells by parthenogenesis wherein stem cells are made from an egg cell without fertilization or SCNT. Combining these patents under one roof should simplify the regenerative medicine patent landscape. The firm intends to license out the animal applications for use in agriculture and animal science and use the human technologies for its internal programs including applications in the retina, vascular system, and dermatology.