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THE ROAD TOWARDS FAR-REACHING THERAPEUTICS THROUGH ILMN, SRPT AND EXEL.

Prohost Biotech - Monday, December 03, 2012

ILLUMINA (ILMN): Illumina is approaching its 52week high. We remind that around June/July 2011  the stock had reached for over $75 to be badly hit because of fear of the bad economy and dwarfing of the healthcare budget, which was relevant. The stock had reached as low as the mid-twenties. At the time we believed this price was an invitation to buy the stock. As a matter of fact ILMN  jumped overnight from around $30 to over $50 following Roche’s offer to buy the firm.      

 We also remind that this firm is still on top of the manufacturer of gene analyzers and the most active and productive from among the group we call “The Genomic Group” together with Life  Technologies (LIFE).  

As we said before, Illumina enables the continued revolution of treatments and is currently leading the way towards personalized medicine.

Rumors about Roche renewing its offering have caused a tremendous increase in ILMN’s call option volume. The fact is that, Roch, or no Roche, Illumina remains the cornerstone of the pharmaceutical revolution.

SAREPTA (SRPT): We agree with the analysts who believe that this firm’s drug eteplirsen for Duchenne muscular dystrophy. should be approved. The key word here is safety and the drug seems safe. We agree also that the FDA has its own rules and regulations regarding accelerated approvals of drugs. But we also believe there is substantial need for such a drug right now. Based on the proof of concept of Sarepta RNA-derived treatments, a  novel difficult technology, and the drug’s positive results on a disease as dangerous and crippling as Duchenne muscular dystrophy, we feel good about the drug and the firm.

Data, indeed, exist that the drug increases the level of dystrophin, which offers the proof of concept towards the fact that the molecules could bring hope to the hopeless children and their families.  

So, the odds of an accelerated approval are favorable towards and, yes, with the condition of conducting a large trial then after for more confirmatory results. 

In any case, the firm’s technology seems to offer safe and effective REN-derived therapeutics – a hard task that took years of the firm’s time, effort and money.

Sarepta is pursuing the same technologies as Alnylam (ANY) and Isis (ISIS), which, if successful, we believe they are the best to create therapeutics that target the root-cause of chronic progressive and life-threatening disease. The successful therapeutics will top the list of drugs that can realize the dream of personalized medicine.

EXELIXIS (EXEL); The approval of COMETRQ for metastatic thyroid cancer is good news for the patients, their physicians and for Exelixis. Why? We will right an article about the positives that came out of this approval.

FORWARD-LOOKING: Material presented here is for informational purposes only. Nothing in this article should be taken as a solicitation to purchase or sell securities. Before buying or selling any stock you should do your own research and reach your own conclusion. Further, these are our 'opinions' and we may be wrong. We may have positions in securities mentioned in this article. You should take this into consideration before acting on any advice given in this article. If this makes you uncomfortable, then do not listen to our thoughts and opinions. The contents of this article do not take into consideration your individual investment objectives so consult with your own financial adviser before making an investment decision. Investing includes certain risks including loss of principal.

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